Episode 162 · Complications

Dissolving fillers and hyaluronidase with Gillian Murray

With Gillian Murray, Prescribing Pharmacist and pharmacist injector, London, UKHosts Dr Jake Sloane and David Segal

About this episode

Gillian Murray is a prescribing pharmacist, clinical researcher and pharmacist injector in London. With over 16 years in the NHS, she is a directorate pharmacist, a senior lecturer in clinical pharmacokinetics, founder of Medicine in Aesthetics and Secretary of the Complications in Medical Aesthetics Collaborative (CMAC). Her interests include hypersensitivity reactions, filler gel chemistry and rheology.

We explore her background and what a prescribing pharmacist is, what hyaluronic acid looks like structurally, natural versus filler HA, crosslinking and BDDE, when we need to dissolve, what hyaluronidase is and how brands differ, on-label versus off-label use, allergy risk and the patch testing debate, emergency and elective protocols, dissolving clinics, and whether ultrasound-guided hyaluronidase is the gold standard.

What you'll learn

  • How hyaluronidase works
  • Crosslinking and BDDE explained
  • Allergy risk and whether to patch test
  • Emergency versus elective dissolving protocols
  • The case for ultrasound-guided dissolving

Topics

  • Hyaluronidase
  • Complications
  • Vascular occlusion
  • Dermal fillers
  • UK

Full transcript

The full transcript for this episode is coming soon.